New

Cellular Longevity ProCapsules

Target signs of aging at the source with clinically proven Mitopure®. Two capsules deliver a provider-exclusive dose of Urolithin A (1000 mg of Mitopure).

Strengthens muscleᵃ

Improves enduranceᵇ

Improves immune fitnessᶜ

Stimulates mitochondrial renewal*

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Related Publications

Clinically proven in numerous trials

Title

Published in

A healthy aging breakthrough

1000mg Pro Dose of Mitopure®

Endurance

17%

Increases leg muscle endurance by up to 17% after 8 weeks.ᵇ

Renewal

Mitochondria

Supports mitochondrial function, mitophagy and biogenesis for healthier, more efficient mitochondria.*

Strength

10%

Increases muscle strength by 10% after 4 months.ᵃ

Recovery

+37%

Lowers creatine kinase levels by 37% 24 hours after exercise compared to baseline.ᵈ

Performance

Improves rate of perceived exertion (RPE) after 4 weeks.ᵈ

Immunity

Immunity

Increases the number of early-responding immune cells and their mitochondrial function after 4 weeks.ᶜ

Endurance

17%

Increases leg muscle endurance by up to 17% after 8 weeks.ᵇ

Renewal

Mitochondria

Supports mitochondrial function, mitophagy and biogenesis for healthier, more efficient mitochondria.*

Strength

10%

Increases muscle strength by 10% after 4 months.ᵃ

Recovery

+37%

Lowers creatine kinase levels by 37% 24 hours after exercise compared to baseline.ᵈ

Performance

Improves rate of perceived exertion (RPE) after 4 weeks.ᵈ

Immunity

Immunity

Increases the number of early-responding immune cells and their mitochondrial function after 4 weeks.ᶜ

Did you know?

Only 1 in 3 people can get enough Urolithin A from diet alone.

Compare to other

The Ultimate Longevity Powerhouse

Comparison criteria
Mitopure
CoQ10

CoQ10

Creatine

Creatine

Spermidine

Spermidine

NMN

NMN

Directly activates mitophagyPartial
Targets a root cause of age-related cellular energy declinePartialPartialPartial
Benefits without exercise
Complete human clinical trialsLimitedLimited

Your cells feel the benefits before you do

Hour 8

Hour 8

Urolithin A levels peak

Mitopure gets right to work. Urolithin A levels increase in the bloodstream, targeting key cells.

Day 2

Day 2

Mitophagy begins

Preclinical data show Mitopure stimulates mitophagy, activating cellular recycling and renewing mitochondria.¹

Day 30

Day 30

Healthy mitochondria form

Mitopure optimizes biogenesis, healthy mitochondria replace damaged ones and immune fitness improves.² ³ ᶜ

Day 60

Day 60

Muscle endurance increases

Leg muscle endurance increases by up to 17% and hand muscle endurance increases by up to 26%.⁴ ⁵ ᵇ

Day 120

Day 120

Increases muscle strength

Muscle cells are reenergized and skeletal muscles are stronger, even without a change in exercise.⁶ ⁷ ᵃ

Day 120+

Day 120+

Studies in progress

Clinical trials are currently studying the benefits of long-term use of Mitopure.⁸

Frequently asked questions

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

a. Clinical studies consistently find improvements in muscle strength and endurance in a varied subset of the population ranging from resistance-trained athletes in their 20s to middle-aged adults with an average BMI of 29.52.

b. Our clinical studies showed that sedentary adults aged 65–90 improved muscle endurance, measured as leg and hand repetitions to fatigue, after daily supplementation with 1,000 mg Mitopure®.

c. Our randomized, placebo-controlled clinical study showed that supplementation with Mitopure® 1,000 mg for 4 weeks was associated with improvements in mitochondrial health of immune cells, favorable shifts in T-cell populations (including naïve cells), and markers of healthy immune function, in healthy, middle-aged adults.

d. Our clinical study showed that trained runners reported lower rate of perceived exertion (RPE) after a 3000 m time trial after 4 weeks of daily supplementation with 1,000 mg Mitopure®, and lower creatine kinase (CK) levels at 1 and 24 hours post-exercise, compared with placebo.

1. Ryu D, Mouchiroud L, Andreux PA, et al. Urolithin A induces mitophagy and prolongs lifespan in C. elegans and increases muscle function in rodents. Nat Med. 2016;22(8):879-888.

2. Andreux PA, Blanco-Bose W, Ryu D, et al. The mitophagy activator urolithin A is safe and induces a molecular signature of improved mitochondrial and cellular health in humans. Nat Metab. 2019;1(6):595-603.

3. Denk D, Singh A, Kasler HG, et al. Effect of the mitophagy inducer urolithin A on age-related immune decline: a randomized, placebo-controlled trial. Nat Aging. 2025;5(11):2309-2322.

4. Monsalve Acevedo A, Sanctuary C, Aitken RJ, Wilkins A, Harrison N, Naughton M. Effects of Urolithin A supplementation on performance and antioxidant status in academy soccer players during preseason: a pilot randomised controlled trial. Front Nutr. 2025;12.

5. Liu S, D’Amico D, Shankland E, et al. Effect of Urolithin A Supplementation on Muscle Endurance and Mitochondrial Health in Older Adults: A Randomized Clinical Trial. JAMA Netw Open. 2022;5(1):e2144279.

6. Zhao H, Zhu H, Yun H, et al. Assessment of Urolithin A effects on muscle endurance, strength, inflammation, oxidative stress, and protein metabolism in male athletes with resistance training: an 8-week randomized, double-blind, placebo-controlled study. J Int Soc Sports Nutr. 2024;21(1):2419388.

7. Singh A, D’Amico D, Andreux PA, et al. Urolithin A improves muscle strength, exercise performance, and biomarkers of mitochondrial health in a randomized trial in middle-aged adults. Cell Rep Med. 2022;3(5).

8. Amazentis SA. A Confirmatory, Randomised, Double-Blind, Placebo-Controlled, Parallel Study to Assess the Effects of a Dietary Supplement Containing Urolithin A (Mitopure®) on Muscle Strength and Performance in Healthy Middle-Aged Adults. clinicaltrials.gov; 2025. Accessed December 17, 2025.

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